The 5 Best Glucosamine & Chondroitin Supplements (2023 Update)

Glucosamine and chondroitin dietary supplements have gotten standard for technique of combating joint pain and stiffness. (1) Given this complement hasn’t been standard or accepted within the scientific neighborhood for very lengthy, it’s not as nicely established as many vitamin supplements. As a result of comparatively new analysis, it may be laborious to know which merchandise are price your cash.

The 2 components you sometimes discover in these dietary supplements — glucosamine, which is normally sourced from shellfish, and chondroitin, which is from cartilage — could have promise when dosed appropriately. They’ll doubtlessly assist those that undergo from joint pain as they each could increase collagen and reduce inflammation. This implies glucosamine and chondroitin dietary supplements could also be particularly nice for individuals who undergo from osteoarthritis. (2) We got here up with an inventory of among the greatest glucosamine and chondroitin dietary supplements available on the market that can assist you determine which one could also be greatest for you.

Greatest Glucosamine Dietary supplements

Editor’s notice: The content material on BarBend is supposed to be informative in nature, but it surely shouldn’t be taken as medical recommendation. The opinions and articles on this web site aren’t supposed to diagnose, forestall, and/or deal with well being issues. It’s at all times a good suggestion to speak to your physician earlier than starting a brand new health, dietary, and/or complement routine. Particular person wants for nutritional vitamins and minerals will fluctuate.

Greatest Glucosamine Complement

We wished our high decide to have a powerful ingredient listing. This decide contains 2000mcg selenium, 500mg of glucosamine, and 100mg of chondroitin, which checked just about all of our packing containers.

Physio Flex Professional

Physio Flex Professional is a brilliant stacked joint complement and goals to advertise mobility, flexibility, lubrication, and power in joints. Along with the five hundred milligrams of glucosamine and 100 milligrams of chondroitin sulfate per two-capsule serving, this complement additionally contains 250mg of ginger extract and 200mg of turmeric. It contains 2000mcg of selenium as nicely, which is named an antioxidant and anti inflammatory and could also be good for lowering joint ache. (3) On high of that, you’ll discover 300mg of bromelain and 100mg of methylsulfonylmethane (MSM), which has been urged to make chondroitin and glucosamine much more efficient for combating osteoarthritis. (4)


Physio Flex Professional Whole Joint Help

Physio Flex Pro Total Joint Support

This joint well being complement is full of the turmeric extract, ginger extract, bromelain, and glucosamine that it’s worthwhile to hold these joints in working order.


The extra f 10mg of Bioperine, or black pepper fruit extract, is necessary as it could make the opposite components extra absorbable by the physique. When you go for a one-month provide of Physio Flex Professional it can value you round $2.00 per serving, which is costlier than another choices available on the market, however this listing of anti-inflammatory and joint health-boosting components makes it extra strong and multifaceted than most others, as nicely. In addition they have bulk purchase choices that go as much as a 5 month provide, which would scale back the value just a little extra in the event you’re engaged on a good funds. 

Who Ought to Purchase Physio Flex Professional

  • Those that worth the addition of MSM, which is a well known potential anti-inflammatory, will just like the 100mg on this method. 
  • Anybody wanting a multifaceted joint complement as this has components that doubtlessly cut back irritation, promote flexibility, assist with mobility, and cut back ache. 
  • Of us who need a affordable serving measurement as this supp requires simply two tablets a day. 

Who Shouldn’t Purchase Physio Flex Professional

  • Anybody on the lookout for a pure glucosamine complement will need to look elsewhere.
  • Of us who don’t get pleasure from taking two tablets per serving.
  • Those that choose powder can discover a powdered complement to stack on this listing.
  • Anybody on a strict funds as this may value you about $2.00 per serving in the event you solely purchase one month upfront. 

Physio Flex Professional takes a multifaceted method to combating joint ache by way of their strong ingredient listing. Though this can be a nice joint complement for anybody, it’s also a stable decide for extra energetic people who need to doubtlessly cut back any irritation of their joints after training, and garner some further assist with their restoration to get back in the gym sooner.

[Related: Could Baking Soda Be The Best Workout Supplement You’ve Never Tried?]

Greatest Easy Method

Typically much less is extra. That is true for Physician’s Greatest Glucosamine, which has six energetic components with none of the fillers or extras to ensure you obtain a wholesome dose of glucosamine with out the fluff.

Physician’s Greatest Glucosamine Chondroitin MSM

Physician’s Greatest gives a glucosamine complement purchasable in both 120-,240-, or 360-capsule bottles. Every four-capsule serving gives 1,500 milligrams of glucosamine and 1,200 milligrams of chondroitin sulfate and is freed from GMOs, soy, and gluten. The easy ingredient listing is meant to advertise joint perform and adaptability, and the 1,000 milligrams of MSM per serving is purified by way of distillation.


Physician’s Greatest Glucosamine Chondroitin MSM

Doctor's Best Glucosamine Chondroitin MSM

An uncomplicated complement with good doses of glucosamine, chondroitin, and methylsulfonylmethane is out there in 120- or 240-capsule bottles. The capsules are non-GMO, gluten and soy-free.


The worth of this specific complement in comparison with different aggressive choices is the simplicity of the ingredient listing. There aren’t any superfluous additions if you’re primarily on the lookout for some glucosamine. If you are going to buy the 120-capsule bottle, you’ll be paying probably the most at about $0.86 per serving. When you go for the 360 capsule bottle, you’ll solely be spending about $0.62 per serving.

Who Ought to Purchase Physician’s Greatest Glucosamine Chondroitin MSM

  • Those that need a glucosamine complement with a brief ingredient listing.
  • Of us who would favor to acquire their glucosamine in bulk.
  • Those that don’t need to pay an arm and a leg for a glucosamine complement. The majority purchase and quick ingredient listing put this product at a good value level. 

Who Shouldn’t Purchase Physician’s Greatest Glucosamine Chondroitin MSM

  • Anybody who needs a better dose of glucosamine per serving.
  • Individuals who would favor having some further components like added vitamin D or hyaluronic acid.
  • Those that don’t get pleasure from taking tablets will need to look elsewhere as this product suggests a 4 tablet serving measurement. 

If you’re at the moment following a every day complement routine and your physician has given you the inexperienced gentle so as to add glucosamine to it, this can be a nice possibility for individuals who don’t need to overcomplicate issues. If the requirement of 4 capsules per serving doesn’t put you off, then significantly take into account including this to your cart.

[Related: The Best Types Of Supplements For Performance, Weight Loss, And Health]

Greatest Glucosamine with Vitamin D

The principle motive to decide on this selection over the remainder of the sector is recommended in its rank, and that’s the addition of 250 % of your every day advisable consumption of vitamin D. 

Transfer Free Vitamin D3, MSM, Glucosamine, and Chondroitin

Every two-tablet serving gives 50 micrograms of vitamin D alongside 1,500 milligrams of glucosamine. You’ll additionally discover 3.3 milligrams of hyaluronic acid, which can assist with further joint lubrication.


Transfer Free Vitamin D3, MSM, Glucosamine and Chondroitin

Move Free Vitamin D3, MSM, Glucosamine and Chondroitin

Every two-tablet serving gives of this complement gives 50 micrograms of Vitamin D alongside 1,500 milligrams of glucosamine. Moreover, there are 3.3 milligrams of hyaluronic acid per serving for higher joint well being.


The extra vitamin D doesn’t come with out some concessions. This complement has a barely elevated calorie rely at 10 calories per serving, which is pretty distinctive in comparison with most calorie-free glucosamine supps. Nevertheless, the value tag on this complement is inexpensive at about $0.41 per serving, making it an inexpensive choice to get your glucosamine and vitamin D repair in a single fell swoop. 

Who Ought to Purchase Transfer Free Vitamin D3, MSM, Glucosamine, and Chondroitin

  • Anybody who must sneak extra vitamin D into their food regimen will like that this gives 250 % of your RDI.
  • Of us who respect a serving measurement of solely two tablets.
  • Those that don’t need to spend an excessive amount of on their complement will respect this price ticket that sits at lower than 50 cents per serving.

Who Shouldn’t Purchase Transfer Free Vitamin D3, MSM, Glucosamine, and Chondroitin

  • Individuals who don’t need their dietary supplements to have any energy.
  • These on the lookout for a extra pure glucosamine complement.

This complement is ideal for individuals who need to reap the potential advantages of including a glucosamine complement to their routine whereas additionally tacking on an added dose of vitamin D — this supp gives a excessive dose of 250 occasions the RDI for vitamin D. 

[Related: Intermittent Fasting 101: A Guide To Benefits, Muscle Gain, And More]

Highest Dosage Glucosamine

When you’re on the lookout for a supp that doesn’t skimp on the glucosamine dosage, look no additional. This method has a whopping 2,250mg of glucosamine per serving (in comparison with the 1,500mg market common), and it is available in at a low value. 

Horbäach Glucosamine Chondroitin with Turmeric & MSM

For these wanting so as to add a considerable amount of glucosamine to their complement routine, Horbäach has you coated. Every three-capsule serving comprises their “superior method joint mix,” consisting of two,250 milligrams of glucosamine and 1,800 milligrams of methylsulfonylmethane (MSM). MSM has been urged in research to be an help for joint ache, irritation, and muscle ache. (5


Horbäach Glucosamine Chondroitin with Turmeric & MSM

Horbäach Glucosamine Chondroitin with Turmeric & MSM

This joint well being complement is very excessive in glucosamine, which can delay the development of osteoarthritis and assist relieve joint ache. Every three-capsule serving gives 2,250 milligrams of glucosamine.


Moreover, the capsules supply 90 milligrams of vitamin C, which can profit your immune system, and 267 milligrams of potassium, which is a vital mineral and an electrolyte. These capsules are lactose, GMO, wheat, and soy-free and exclude all artificial sweeteners and preservatives. Contemplating how excessive the glucosamine dose is, the value tag is noticeably decrease than lots of the competing choices available on the market at simply $0.28 cents per serving.

Who Ought to Purchase Horbäach Glucosamine Chondroitin with Turmeric & MSM

  • Those that need a very excessive dose of glucosamine per serving will like the two,250mg current right here.
  • Anybody who must hold their complement spending down — this product prices lower than 30 cents per serving.
  • Of us who’re glad to have the additional vitamin C of their glucosamine complement, which may help promote a wholesome immune system.

Who Shouldn’t Purchase Horbäach Glucosamine Chondroitin with Turmeric & MSM

  • Anybody who doesn’t want such a excessive glucosamine dose in a single serving.
  • Individuals who would fairly have Vitamin D as a substitute of Vitamin C alongside their glucosamine.

With 60 servings per bottle, every capsule is available in at eight cents. That form of worth is plain in comparison with the remainder of the sector when wanting strictly at glucosamine dose. If you’re available on the market for a dose this excessive, it could be fairly laborious to argue towards this selection.

[Related: Best Macros Calculator For Tracking Muscle Gain And Fat Loss]

Highest MSM Glucosamine Complement

As you sift by way of all of the glucosamine choices available on the market, this specific complement will stand out for top MSM content material, which can additionally help in combating muscle and joint stiffness, in addition to irritation. 

Zenwise Glucosamine Chondroitin Sulfate MSM Curcumin

Zenwise glucosamine goals to advertise mobility, flexibility, lubrication, and power within the hip joint. Along with the 1,500 milligrams of glucosamine and 1,200 milligrams of chondroitin sulfate per three-capsule serving, this complement additionally contains 100 milligrams of curcumin and 25 milligrams of hyaluronic acid. In line with a 2017 research in Meals, curcumin may help handle exercise-induced inflammation and muscle soreness, which might make for improved recovery and efficiency. (3)


Zenwise Well being Superior Energy Joint Help

Zenwise Health Advanced Strength Joint Support

This joint well being complement gives 30 three-capsule servings that encompass 1,500 milligrams of glucosamine and 1,200 milligrams of chondroitin. It additionally contains curcumin (250 milligrams), hyaluronic acid (25 milligrams).


Hyaluronic acid could play a task in cushioning and lubricating the physique as probably the most versatile macromolecule current within the connective tissues of all vertebrae, in keeping with a evaluate in Advances in Meals and Diet Analysis. Hyaluronic acid can be discovered within the joints, eyes, and coronary heart valves. (4) This supp has a three-tablet serving measurement, so in the event you’re tablet averse, it is probably not the complement for you. Nevertheless, in the event you can deal with tablets, the $0.49 value per serving is an actual bonus.

Who Ought to Purchase Zenwise Glucosamine Chondroitin Sulfate MSM Curcumin

  • Those that worth the addition of curcumin to their glucosamine complement to assist help train restoration.
  • Anybody working with a tighter funds as this product is lower than 50 cents per serving.
  • Of us who need the added hyaluronic acid of their complement routine for potential lubrication of connective tissue.

Who Shouldn’t Purchase Zenwise Glucosamine Chondroitin Sulfate MSM Curcumin

  • Anybody on the lookout for a pure glucosamine complement will need to look elsewhere.
  • Of us who don’t get pleasure from taking three tablets per serving.
  • Those that choose powder can discover a powdered complement to stack elsewhere.

There may be a lot to love about Zenwise’s complement, from its general dosage to added components that may help the glucosamine. This can be a nice pick-up for extra energetic people who need to doubtlessly cut back the irritation of their joints after training, and garner some further assist with their restoration to get back in the gym sooner.

[Related: Nutrition For Bulking: 10 Tips For Intelligent Muscle Gain]

Advantages of Glucosamine and Chondroitin Dietary supplements

These are two separate components: glucosamine, which is derived from shellfish and should barely delay the development of osteoarthritis and relieve pain; and chondroitin, a chemical discovered primarily in joint cartilage. Some analysis signifies that this complement could assist to cut back ache and bone degradation attributable to osteoarthritis. (6)(7

A research printed in Medication & Growing older in 2007 concluded, “there’s compelling proof that glucosamine sulfate and chondroitin sulfate could intrude with the development of (osteoarthritis).” (8) Plainly chondroitin is extra intently linked with reducing joint swelling. Glucosamine may help with ache and should intrude with osteoarthritis development.

[Related: The Lifter’s Guide To Magnesium: What This Nutrient Does For Strength]

How We Selected the Greatest Glucosamine and Chondroitin Dietary supplements

We frolicked wanting by way of numerous glucosamine merchandise to decipher which of them had been our favorites. We thought of value, ingredient listing, and dosage to construct this listing. 

Worth

We picked out glucosamine dietary supplements that ranged between round $0.20 and $0.60 per serving. Though glucosamine prices much less on common than different dietary supplements like multivitamins, value continues to be an necessary consideration, and the prices can add up if you’re stocking up month-to-month.

One of many main components that influences value is the ingredient listing. An in depth ingredient listing normally yields a better value level, whereas an easier ingredient listing or a complement with much less high quality components will usually be at a lower cost level. Though value is a vital issue, integrity behind a product at all times comes first in our eyes — and on this listing.

Ingredient Record

Ingredient listing is one other issue we thought of when placing collectively this listing. We picked some supps with easy components and no further frills, and we additionally selected some with a extra intensive ingredient listing to assist meet the wants of all clients.

Knee Pain
Picture through Shutterstock/TORWAISTUDIO

A few of the picks are geared in direction of extras which will assist meet particular wants — like further vitamin D or vitamin C — whereas some are simply geared in direction of a excessive dose of glucosamine. Relaxation assured, we picked a diversified listing of dietary supplements, so there must be one thing for everybody.

Dosage

The quantity of glucosamine current will fluctuate from method to method, as will the wants of the buyer. Most of those picks have 1,500mg of glucosamine in them, which is about common throughout the market. Now we have one decide that stands out from the remaining with a better dosage of round 2,250mg per serving, which could possibly be a profitable issue for some. 

There are additionally a number of picks with dosages of different components that could be engaging. A few of the picks include chondroitin, vitamins C and D, or MSM. We also have a decide that has added turmeric, which has been urged in some research to cut back irritation (5). Whether or not you’re on the lookout for a simple hit of glucosamine, a extra spectacular dose of two,250mg, or a high dose of vitamin D, there’s a decide that’s best for you on this listing. 

How A lot Do Glucosamine and Chondroitin Value Dietary supplements Value?

With how necessary it’s to deal with and help your joints, it could be a welcome shock that the majority glucosamine dietary supplements are fairly cheap, particularly when in comparison with different sorts of merchandise like protein powders and pre-workouts. The worth per serving in addition to container value is comparatively low-cost for these merchandise, however most of them have instructions to take a number of servings per day which might drive up the associated fee with every bottle not lasting so long as you will have initially thought. 

Greatest Glucosamine Complement Physio Flex Professional $58.00

Per serving: $1.93

Greatest Easy Method Physician’s Greatest Glucosamine Chondroitin MSM $25.48

Per serving: $0.42

Greatest Glucosamine with Vitamin D Transfer Free Vitamin D3, MSM, Glucosamine, and Chondroitin $23.99

Per serving: $0.40

Highest Dosage Glucosamine Horbäach Glucosamine Chondroitin with Turmeric & MSM $19.99

Per serving: $0.33

Highest MSM Glucosamine Complement Zenwise Glucosamine Chondroitin Sulfate MSM $39.99

Per serving: $0.67

For a container of glucosamine and chondroitin, you’ll be able to count on to pay between $20 and $60 with the associated fee per serving round $0.33 to $1.93. If it’s worthwhile to take a number of servings per day although it is best to issue that in as a result of the every day value will likely be double what the associated fee per serving is that if it’s worthwhile to take one serving within the morning and one within the night.

What To Think about Earlier than Shopping for Glucosamine and Chondroitin

There are a number of components to think about earlier than including glucosamine to your complement stack. We increase on dosage, value, allergy symptoms and lifestyle choices, and formation beneath.

Dosage and Effectiveness

You’ll need to be sure that your glucosamine complement has a dosage that meets your wants as a shopper. Analysis places the simplest dose at a minimal of 1,500mg of glucosamine daily (9). Each decide on this listing has not less than 1,500mg of glucosamine per serving, whereas some have over 2,000mg. 

A person with muscular shoulders facing away.
Picture viat: Roman Chazov / Shutterstock

Many of the research round glucosamine have been carried out on glucosamine alone, however the research which have been carried out on animals with glucosamine together with chondroitin appear to be extra promising than these for glucosamine alone (9). It will be crucial to see human research as a way to make an efficient name on effectiveness, however thus far it appears these two dietary supplements could also be extra highly effective when taken synergistically.

Worth

The worth on glucosamine is pretty affordable throughout the board, however it’s nonetheless an necessary issue when deciding which supp may be best for your lineup. Glucosamine ranges in value relying on further components and dosage. Our most costly possibility on this listing is about $0.62 per serving, but when that appears like greater than you need to spend, there are alternatives that value far much less that also pack a stable punch of glucosamine — you might simply be extra restricted in further components.

pistol squat
Picture through Shutterstock / thedesailifestyle

On the whole, a sturdy ingredient listing, the standard of the components, and better dosages could find yourself costing extra. If it’s simply glucosamine that you simply’re after, there are very simple straight-forward glucosamine supps on this listing that come at an especially inexpensive charge. 

Allergy symptoms and Way of life

Allergy symptoms and your way of life are each essential components to think about in relation to glucosamine supplementation. Since glucosamine is sourced from shellfish, it’s not an appropriate complement for vegans or vegetarians.

Glucosamine
Picture through Shutterstock/Farion_O

It’s suggested that those that undergo from shellfish allergy symptoms or those that hold Kosher ought to keep away from glucose dietary supplements, as nicely. Though we have now not tried any, there are alternatives for shellfish-free glucosamine, however it’s at all times greatest to verify together with your physician earlier than deciding so as to add any kind of glucosamine to your complement stack. 

Kind

The formulations of our picks for glucosamine fluctuate. Though most are available tablet type, there are some picks which have a single-pill dose whereas some require 5 tablets per dose. If tablets aren’t your factor, you might need to go for a serving measurement that’s one or two tablets per serving or discover a powder option.

[Related: IIFYM (If It Fits Your Macros): Your Ultimate Guide To This Diet]

Remaining Phrase

Research have urged that glucosamine could also be a useful complement to take in the event you undergo from joint ache and stiffness, osteoarthritis, or inflammation. (9) This listing gives the framework for a couple of distinctive selections that vary from easy formulation, glucosamine with extras like vitamin D, and a few which are paired with different components like chondroitin, which can maximize advantages. The hardest half about making it by way of this listing is deciding which one is greatest designed to suit your wants.

With a handful of nice selections at your disposal, you’ll simply have to think about your way of life, your funds, the dosage you’re after, and what number of tablets you’re prepared to take to make your best option for your self. Keep in mind, it’s at all times a good suggestion to speak together with your well being care supplier earlier than committing to a brand new complement. However upon getting every thing sorted, this listing generally is a nice information. 

FAQs

Will glucosamine assist alleviate my joint ache?

It isn’t assured that glucosamine will alleviate joint ache and stiffness; nonetheless, research counsel that it could be a useful help when combating joint ache. (2) It’s at all times greatest to seek the advice of together with your healthcare supplier in the event you suppose this complement could also be best for you or if you wish to attempt it out to see if it may be an efficient possibility to your joint ache.

What’s the greatest glucosamine and chondroitin complement?

There are various completely different glucosamine dietary supplements and a few embrace completely different added components which will assist with joint help and irritation comparable to curcumin, MSM, and vitamin D. That stated, our favourite is Physio Flex Professional. It comprises a stable dose of glucosamine and chondroitin together with different potential irritation fighters comparable to selenium, bromelain, MSM, and Bioperine.

How a lot glucosamine ought to I take every day?

The present advice for every day consumption for joint aid is a minimal of 1,500mg a day. (9) That is the urged quantity to take for doubtlessly relieving joint ache and irritation. Each decide on this listing has not less than 1,500mg of glucosamine per serving, if no more.

How a lot will glucosamine value me?

Glucosamine is a comparatively cheap complement in comparison with another staples, like pre-workout or protein. When you undergo from irritation, or joint ache and stiffness, glucosamine could also be an affordable resolution. Our picks on this listing value round $0.33 and $1.93 per serving.

References

  1. Zhu X, Sang L, Wu D, Rong J, Jiang L. Effectiveness and security of glucosamine and chondroitin for the remedy of osteoarthritis: a meta-analysis of randomized managed trials. J Orthop Surg Res. 2018 Jul 6;13(1):170. doi: 10.1186/s13018-018-0871-5. PMID: 29980200; PMCID: PMC6035477.
  2. Henrotin Y, Marty M, Mobasheri A. What’s the present standing of chondroitin sulfate and glucosamine for the remedy of knee osteoarthritis? Maturitas. 2014 Jul;78(3):184-7. doi: 10.1016/j.maturitas.2014.04.015. Epub 2014 Might 1. Erratum in: Maturitas. 2014 Dec;79(4):487. PMID: 24861964.
  3. Rayman MP. Selenium and human well being. Lancet. 2012 Mar 31;379(9822):1256-68. doi: 10.1016/S0140-6736(11)61452-9. Epub 2012 Feb 29. PMID: 22381456.
  4. Lubis AMT, Siagian C, Wonggokusuma E, Marsetyo AF, Setyohadi B. Comparability of Glucosamine-Chondroitin Sulfate with and with out Methylsulfonylmethane in Grade I-II Knee Osteoarthritis: A Double Blind Randomized Managed Trial. Acta Med Indones. 2017 Apr;49(2):105-111. PMID: 28790224.2014;72:137-176. doi: 10.1016/B978-0-12-800269-8.00009-9. PMID: 25081082.
  5. Butawan M, Benjamin RL, Bloomer RJ. Methylsulfonylmethane: Purposes and Security of a Novel Dietary Complement. Vitamins. 2017 Mar 16;9(3):290. doi: 10.3390/nu9030290. PMID: 28300758; PMCID: PMC5372953.
  6. Deal CL, Moskowitz RW. Nutraceuticals as therapeutic brokers in osteoarthritis. The position of glucosamine, chondroitin sulfate, and collagen hydrolysate. Rheum Dis Clin North Am. 1999 Might;25(2):379-95. doi: 10.1016/s0889-857x(05)70074-0. PMID: 10356424.
  7. Black C, Clar C, Henderson R, MacEachern C, McNamee P, Quayyum Z, Royle P, Thomas S. The medical effectiveness of glucosamine and chondroitin dietary supplements in slowing or arresting development of osteoarthritis of the knee: a scientific evaluate and financial analysis. Well being Technol Assess. 2009 Nov;13(52):1-148. doi: 10.3310/hta13520. PMID: 19903416.
  8. Bruyere O, Reginster JY. Glucosamine and chondroitin sulfate as therapeutic brokers for knee and hip osteoarthritis. Medication Growing older. 2007;24(7):573-80. doi: 10.2165/00002512-200724070-00005. PMID: 17658908.
  9. Dahmer S, Schiller RM. Glucosamine. Am Fam Doctor. 2008 Aug 15;78(4):471-6. PMID: 18756654.

 

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